Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response
نویسندگان
چکیده
منابع مشابه
Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response.
BACKGROUND Atopic dermatitis (AD) is a common inflammatory skin disease exhibiting a predominantly T(H)2/"T22" immune activation and a defective epidermal barrier. Narrow-band UVB (NB-UVB) is considered an efficient treatment for moderate-to-severe AD. In patients with psoriasis, NB-UVB has been found to suppress T(H)1/T(H)17 polarization, with subsequent reversal of epidermal hyperplasia. The ...
متن کاملNarrow-band UVB treatment in atopic dermatitis.
MATERIAL AND METHODS Fig. 1. Narrow-band UVB (NB-UVB) and combined UVAB treatTen adult patients (mean age 27 years) with symmetrical AD were ment results in half-side comparison study in 10 patients with atopic included in the half-side (right/left) comparison study. One side of the dermatitis ( 5 NB-UVB; 5 UVAB). body was treated with narrow-band UVB, the other with combined UVAB. The light so...
متن کاملUVB phototherapy of atopic dermatitis.
UVB phototherapy of atopic dermatitis was investigated in two paired-comparison studies. In study I, 17 patients were treated for 8 weeks with ultraviolet B radiation (UVB) on one half of the body and with visible light (placebo) on the other. A severity score based on eight clinical variables was determined before, during and after treatment. The total score, pruritus score and overall evaluat...
متن کاملUVA/UVB phototherapy for atopic dermatitis revisited.
BACKGROUND Atopic dermatitis (AD) is a genetically determined pruritic skin disease affecting predominantly young people. The therapy of AD includes mainly corticosteroids (CS), antihistamines and immunosuppressors. CS are known to cause a variety of side effects and attempts have been made to reduce or eliminate their use through alternative methods such as phototherapy (UVA/UVB, UVA(1), UVB 3...
متن کاملNarrow band UVB phototherapy in dermatology.
The first report of the use of ‘phototherapy’ in the treatment of skin disorders dates from 1400 BC from India when patients with vitiligo were given certain plant extracts (whose active ingredients included psoralens) and then exposed to the sun. The real interest in the use of ultraviolet (UV) irradiation in the treatment of various skin diseases started in the 19 century when Niels Finsen re...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2011
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2011.05.042